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  1. Lepirudin

    Hirudin variant-1 Lepirudin is identical to natural hirudin except for substitution of leucine for isoleucine at the N-terminal end of the molecule and the absence of a sulfate group on the tyrosine at position 63. It is produced via yeast cells. For the ...

  2. Bivalirudin

    Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intrav ...

  3. Leuprolide

    Leuprorelin Leuprolide belongs to the general class of drugs known as hormones or hormone antagonists. It is a synthetic 9 residue peptide analog of gonadotropin releasing hormone. Leuprolide is used to treat advanced prostate cancer. It is also used to t ...

  4. Peginterferon alfa-2a

    Human interferon 2a, is a covalent conjugate of recombinant alfa-2a interferon with a single branched bis-monomethoxy polyethylene glycol (PEG) chain. The PEG moiety is linked at a single site to the interferon alfa moiety via a stable amide bond to lysin ...

  5. Sermorelin

    Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH or GRF) consisting of 44 amino aci ...

  6. Interferon alfa-n1

    Interferon alpha-2 Interferon alpha-A LeIF A Purified, natural (n is for natural) glycosylated human interferon alpha proteins 166 residues For treatment of venereal or genital warts caused by the Human Papiloma Virus Immunomodulatory Agents Antiviral Age ...

  7. Darbepoetin alfa

    Epoetin Erythropoietin precursor Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. For the treatment of anemia ( ...

  8. Goserelin

    Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer ...

  9. Epoetin alfa

    Epoetin Erythropoietin precursor Human erythropoietin (recombinant), produced by CHO cells. For treatment of anemia (from renal transplants or certain HIV treatment) Antianemic Agents Binding of erythropoietin to the erythropoietin receptor leads to recep ...

  10. Salmon Calcitonin

    Calcitonin 1 precursor Calcitonin-salmon Calcitonin, salmon Salmotonin Synthetic peptide, 32 residues long formulated as a nasal spray. For the treatment of post-menopausal osteoporosis Antiosteporotic Agents Bone Density Conservation Agents Antihypercalc ...

  11. Interferon alfa-n3

    Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). For the intralesional treatment of refractory or recur ...

  12. Pegfilgrastim

    G-CSF Granulocyte colony-stimulating factor precursor Lenograstim Pluripoietin PEGylated (at N terminus) form of human G-CSF (Granulocyte colony stimulating factor), 175 residues, produced from E. coli via bacterial fermentation. Increases leukocyte produ ...

  13. Sargramostim

    Colony-stimulating factor CSF GM-CSF Granulocyte-macrophage colony-stimulating factor precursor Molgramostin Human, recombinant GM-CSF, expressed in yeast. Glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein. ...

  14. Secretin

    Secremax, SecreFlo This drug is the synthetic form of natural secretin. It is prepared using solid phase peptide synthesis. Secretin is a peptide hormone produced in the S cells of the duodenum. Its main effect is to regulate the pH of the small intestine ...

  15. Peginterferon alfa-2b

    Peginterferon alfa-2b is a covalent conjugate of recombinant alfa-2b interferon with monomethoxy polyethylene glycol (PEG). The average molecular weight of the PEG portion of the molecule is 12,000 daltons. The average molecular weight of the PEG-Intron m ...